BDBM50536667 CHEMBL4559614

SMILES CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Cl)c2c(N)ncnc12

InChI Key InChIKey=BYNIEOFYNNLCCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536667   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50536667(CHEMBL4559614)
Affinity DataIC50: 28nMAssay Description:Inhibition of human 6His-tagged DOT1L (1 to 420 residues) measured after 30 mins by AlphaScreen binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed