BDBM50537285 CHEMBL4570327

SMILES COc1ccc2OCC(Cc2c1)C(=O)Nc1ccc(cc1OCCN(C)C)-c1c[nH]nc1C

InChI Key InChIKey=JEZPZXAMLGEGDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537285   

TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537285(CHEMBL4570327)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537285(CHEMBL4570327)
Affinity DataIC50: 16nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed