BDBM50537288 CHEMBL4552537

SMILES COc1ccc2OC[C@H](Cc2c1)C(=O)Nc1ccc(cc1OCCN(C)C)-c1ccncc1

InChI Key InChIKey=MGSFSBWPBXVAEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537288   

TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537288(CHEMBL4552537)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537288(CHEMBL4552537)
Affinity DataIC50: 68nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed