BDBM50537291 CHEMBL4555191

SMILES CN1C(=O)[C@@]2(Cc3ccc(C[C@@]45SS[C@@](CO)(N(C)C4=O)C(=O)N5C)cc3)SS[C@]1(CO)C(=O)N2C

InChI Key InChIKey=WGLWNZBIJQLQOG-GXRSIYKFSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537291   

TargetHistone acetyltransferase p300/Hypoxia-inducible factor 1-alpha(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50537291(CHEMBL4555191)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human fluorescein-labeled HIF-1alpha (786 to 826 residues)/ human GST-fused p300 CH1 domain (323 to 423 residues) protein-protein inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50537291(CHEMBL4555191)
Affinity DataKd:  750nMAssay Description:Binding affinity to human GST-fused p300 CH1 domain (323 to 423 residues) under hypoxic condition by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed