BDBM50537595 CHEMBL4642101::US11149020, Compound 4 (MW-177)

SMILES CCN(CC)c1cc(-c2ccncc2)c(nn1)-c1ccccc1

InChI Key InChIKey=JMOIAQYMVKBXJO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50537595   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537595(CHEMBL4642101 | US11149020, Compound 4 (MW-177))
Affinity DataIC50:  238nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537595(CHEMBL4642101 | US11149020, Compound 4 (MW-177))
Affinity DataIC50:  369nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537595(CHEMBL4642101 | US11149020, Compound 4 (MW-177))
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537595(CHEMBL4642101 | US11149020, Compound 4 (MW-177))
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase P236LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537595(CHEMBL4642101 | US11149020, Compound 4 (MW-177))
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase V106AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed