BDBM50537597 CHEMBL4645737::US11149020, Compound 6 (MW-105)

SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1ccccc1

InChI Key InChIKey=JZNLARIEJUCAJO-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50537597   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537597(CHEMBL4645737 | US11149020, Compound 6 (MW-105))
Affinity DataKi:  657nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537597(CHEMBL4645737 | US11149020, Compound 6 (MW-105))
Affinity DataIC50:  710nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537597(CHEMBL4645737 | US11149020, Compound 6 (MW-105))
Affinity DataIC50:  490nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537597(CHEMBL4645737 | US11149020, Compound 6 (MW-105))
Affinity DataIC50:  8.02E+3nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537597(CHEMBL4645737 | US11149020, Compound 6 (MW-105))
Affinity DataIC50:  543nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537597(CHEMBL4645737 | US11149020, Compound 6 (MW-105))
Affinity DataIC50:  843nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent