BDBM50537602 CHEMBL4640881::US11149020, Compound 50 (MW-017)
SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccc(F)cc2c1
InChI Key InChIKey=JFIFTUZQRREXAJ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50537602
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 974nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 1.68E+4nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 710nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair