BDBM50537607 CHEMBL4635988::US11149020, Compound 61 (MW-086)

SMILES C1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1

InChI Key InChIKey=HEDDEYUBLWOYBE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50537607   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537607(CHEMBL4635988 | US11149020, Compound 61 (MW-086))
Affinity DataIC50: >2.00E+4nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537607(CHEMBL4635988 | US11149020, Compound 61 (MW-086))
Affinity DataIC50:  9.09E+3nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537607(CHEMBL4635988 | US11149020, Compound 61 (MW-086))
Affinity DataIC50:  9.13E+3nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537607(CHEMBL4635988 | US11149020, Compound 61 (MW-086))
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537607(CHEMBL4635988 | US11149020, Compound 61 (MW-086))
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed