BDBM50538008 CHEMBL4638732
SMILES [H][C@]12C[C@@]1([H])N[C@H](COc1cncc(Cl)c1)C2
InChI Key InChIKey=DMDCNPUUEFFDRN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50538008
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in IMR32 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 2 min in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 min in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair