BDBM50538208 CHEMBL4648071

SMILES Fc1ccc(NC(=O)O[C@H]2CN3CCC2CC3)c(c1)-c1cccc(Cl)c1

InChI Key InChIKey=OUUOAZNFNHOROT-IBGZPJMESA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50538208   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50538208(CHEMBL4648071)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor transiently expressed in HEK293T cell membranes incubated for 1 hr by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50538208(CHEMBL4648071)
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor transiently expressed in HEK293T cell membranes incubated for 1 hr by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50538208(CHEMBL4648071)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M2 receptor transiently expressed in HEK293T cell membranes incubated for 1 hr by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50538208(CHEMBL4648071)
Affinity DataEC50:  27nMAssay Description:Antagonist activity at muscarinic M3 receptor (unknown origin) expressed in HEK293 cells coexpressing EA tagged beta-arrestin2 assessed as inhibition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50538208(CHEMBL4648071)
Affinity DataEC50:  17nMAssay Description:Antagonist activity at human muscarinic M3 receptor expressed in HEK293 assessed as inhibition of carbachol-induced IP1 accumulation preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed