BDBM50538407 CHEMBL4647621::US11236045, Example 22
SMILES O=C(Nc1c2CCCc2cc2CCCc12)NS(=O)(=NC#N)c1ccccc1
InChI Key InChIKey=UZIPRJJBZBJTBL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50538407
Affinity DataIC50: 21nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair