BDBM50538708 CHEMBL4632436

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1ccccc1Cl

InChI Key InChIKey=ZWAGEDFCAJXKDS-UHFFFAOYSA-N

Data  11 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50538708   

TargetCarbonic anhydrase 7(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human CA7 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 7(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  2.90nMAssay Description:Inhibition of recombinant human CA7 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  5.60nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  5.60nMAssay Description:Inhibition of recombinant human CA2 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  62nMAssay Description:Inhibition of full length human CA9 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  62nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  63nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  63nMAssay Description:Inhibition of full length human CA12 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  86nMAssay Description:Inhibition of human CA14 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  94nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50538708(CHEMBL4632436)
Affinity DataKi:  94nMAssay Description:Inhibition of recombinant human CA1 incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed