BDBM50538825 CHEMBL4642529

SMILES CN(C)C[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(nc12)-c1cc(Cl)c(O)c(Cl)c1)C#N

InChI Key InChIKey=DRCFASQQJKFJFY-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538825   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Stanford University

Curated by ChEMBL

LigandBDBM50538825(CHEMBL4642529)Copy SMILESCopy InChI

Affinity DataEC50:  45nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/12/2021
Entry Details Article
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