BDBM50539188 CHEMBL4637222

SMILES Cc1cc(C)c(cc1NC(=O)c1ccc(OCc2ccccn2)cc1)-c1cn(C)cn1

InChI Key InChIKey=SMQVBAGSZVHCJP-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50539188   

TargetSmoothened homolog(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataEC50:  2.60nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataEC50:  3.10nMAssay Description:Binding affinity to mouse SMOMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataEC50:  1.5nMAssay Description:Binding affinity to human SMOMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed