BDBM50540018 CHEMBL4642335

SMILES Cn1cc(cn1)-c1cnc(NCc2c3CCOc3ccc2F)n2cnc(c12)S(C)(=O)=O

InChI Key InChIKey=IEJBULVHHQXFQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540018   

TargetPolycomb protein EED(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540018(CHEMBL4642335)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed