BDBM50540066 CHEMBL4639107::US11407749, Example 5

SMILES Cc1c(cccc1-c1ccccc1)-c1cn2nc(CNCCO)cnc2n1

InChI Key InChIKey=SIYAOZFRXTVXSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540066   

LigandPNGBDBM50540066(CHEMBL4639107 | US11407749, Example 5)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540066(CHEMBL4639107 | US11407749, Example 5)
Affinity DataIC50: 100nMAssay Description:Antagonist activity against PDL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed