BDBM50540068 CHEMBL4636342::US11673883, Example 1

SMILES O[C@H]1C[C@H](C1)NC1CCN(CC1)c1cccc(-c2ccc3OCCOc3c2)c1C#N

InChI Key InChIKey=GDSCQNIOXNHQHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540068   

TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540068(CHEMBL4636342 | US11673883, Example 1)
Affinity DataIC50: 100nMAssay Description:Antagonist activity against PDL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM50540068(CHEMBL4636342 | US11673883, Example 1)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent