BDBM50540267 CHEMBL4639986

SMILES C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(CN4CCOCC4)cc3)nc3ccsc23)c1

InChI Key InChIKey=MATMLMQAUYFNDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540267   

TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540267(CHEMBL4639986)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50540267(CHEMBL4639986)
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed