BDBM505404 (S)-6-((benzo[d]thiazol-7-yl(1-(1- cyanocyclopropyl)-1H-1,2,3-triazol- 4-yl)methyl)amino)-4- (neopentylamino)quinoline- 3,8-dicarbonitrile::BDBM505458::US11066414, Compound 67

SMILES CC(C)(C)CNc1c(C#N)cnc2c(C#N)cc(N[C@H](C3=CN(C4(C#N)CC4)NN3)c3cccc4ncsc34)cc12

InChI Key InChIKey=KHNRORJMYRKXQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505404   

TargetEpidermal growth factor receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 505404BDBM505404((S)-6-((benzo[d]thiazol-7-yl(1-(1- cyanocyclopropy...)
Affinity DataIC50: 1nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 505404BDBM505404((S)-6-((benzo[d]thiazol-7-yl(1-(1- cyanocyclopropy...)
Affinity DataIC50: 3nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2021
Entry Details
US Patent