BDBM50540736 CHEMBL4645145

SMILES Fc1cccc(-c2ccc3[nH]nc(C(=O)NC4CCS(=O)(=O)CC4)c3c2)c1F

InChI Key InChIKey=RLUSWBPHYRGQKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540736   

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540736(CHEMBL4645145)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540736(CHEMBL4645145)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed