BDBM50541073 CHEMBL4632565

SMILES Cc1ccc2nc([nH]c2c1)-c1cccc(NC(=O)CCc2ccccc2)c1

InChI Key InChIKey=BCWAEMAJIICXQI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50541073   

TargetMatrix metalloproteinase-9(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541073BDBM50541073(CHEMBL4632565)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of recombinant human MMP9 catalytic domain (Phe107 to Pro449 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541073BDBM50541073(CHEMBL4632565)
Affinity DataIC50: 2.84E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
Target72 kDa type IV collagenase(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541073BDBM50541073(CHEMBL4632565)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) expressed in yeast cells using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541073BDBM50541073(CHEMBL4632565)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human MMP8 catalytic domain (Phe99 to Gln269 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541073BDBM50541073(CHEMBL4632565)
Affinity DataIC50: 3.64E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541073BDBM50541073(CHEMBL4632565)
Affinity DataIC50: 4.63E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCollagenase 3(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541073BDBM50541073(CHEMBL4632565)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asn274 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed