BDBM50541260 CHEMBL4647552

SMILES COC1CCN(C(=O)Nc2ccc(-c3ccc(-c4c[nH]c([C@@H]5CCCN5C(=O)[C@H](NC(=O)N5CC[C@@H](NC(=O)OCc6ccccc6)C5)c5ccccc5)n4)cc3)cc2)CC1

InChI Key InChIKey=XFKWGSIYZFJIRL-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541260   

TargetNonstructural protein 5A(Hepacivirus C)
Japan Tobacco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541260BDBM50541260(CHEMBL4647552)
Affinity DataEC50:  0.0180nMAssay Description:Inhibition of NS5A in Hepatitis C virus subtype 2a replicon infected in human HuH7 cells assessed as reduction in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Japan Tobacco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541260BDBM50541260(CHEMBL4647552)
Affinity DataEC50:  0.0280nMAssay Description:Inhibition of NS5A in Hepatitis C virus subtype 1b replicon infected in human HuH7 cells assessed as reduction in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Japan Tobacco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541260BDBM50541260(CHEMBL4647552)
Affinity DataEC50:  0.0390nMAssay Description:Inhibition of NS5A in Hepatitis C virus subtype 1a replicon infected in human HuH7 cells assessed as reduction in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed