BDBM50541274 CHEMBL4643315

SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccncc2)c1

InChI Key InChIKey=HRELGTDDFADJJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541274   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541274(CHEMBL4643315)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541274(CHEMBL4643315)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed