BDBM50542061 CHEMBL4634148
SMILES NC(=O)C([C@@H]1CCN(CCOc2ccc(cc2)-c2nccs2)C1)(c1ccccc1)c1ccccc1
InChI Key InChIKey=KMXFISMMVQHBPO-RUZDIDTESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50542061
Affinity DataKi: 597nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 603nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR4 receptor expressed in Jurkat cells incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 622nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair