BDBM50542061 CHEMBL4634148

SMILES NC(=O)C([C@@H]1CCN(CCOc2ccc(cc2)-c2nccs2)C1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=KMXFISMMVQHBPO-RUZDIDTESA-N

Data  2 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50542061   

TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataKi:  597nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataKi:  603nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR4 receptor expressed in Jurkat cells incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50:  631nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542061(CHEMBL4634148)
Affinity DataIC50:  622nMAssay Description:Antagonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as reduction in beta-arrestin recruitment incubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed