BDBM50543243 CHEMBL4636139

SMILES CN1CCN(CC1=O)C(=O)C1CCN(C1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=GSWKVEFNZIDKIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543243   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50543243(CHEMBL4636139)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed