BDBM50543442 CHEMBL4645450

SMILES CNCc1ncc(-c2ccc(Oc3cc(Cl)ccc3CN3[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@]4(Cc5ccc(Cl)cc5)CCCN(C4)C(=O)[C@H](Cc4ccccc4)CC3=O)cc2)n1C

InChI Key InChIKey=SHRDFKRZLQQOII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543442   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543442(CHEMBL4645450)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed