BDBM50543444 CHEMBL4641251

SMILES CNCc1ncc(-c2ccc(Oc3cc(Cl)cc(F)c3CN3[C@@H](C)C(=O)N[C@@H](COC)C(=O)N(C)[C@@]4(Cc5ccc(Cl)cc5)CCCN(C4)C(=O)[C@H](CC(F)(F)F)CC3=O)cc2)n1C

InChI Key InChIKey=GZHXJDZJHHTOKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543444   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543444(CHEMBL4641251)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed