BDBM50543600 CHEMBL4639853

SMILES Cc1cc(Nc2cc(Cl)nc(Oc3ccc(cc3)[N+]([O-])=O)n2)n[nH]1

InChI Key InChIKey=CEUMAXLRGBKFQP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50543600   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50:  40nMAssay Description:Inhibition of Vps34 in human MCF7-LC3 cells assessed as rapamycin-induced autophagyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50:  90nMAssay Description:Inhibition of Vps34 in human MCF7-LC3 cells assessed as starvation-induced autophagyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50:  19nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technical University Dortmund

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50:  2nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543600(CHEMBL4639853)
Affinity DataIC50:  19nMAssay Description:Inhibition of Vps34 in human MCF7-LC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed