BDBM50544085 CHEMBL4642177

SMILES CCC(=O)Nc1cc(Nc2nccc(n2)-c2c[nH]c3c(CCO)cccc23)c(OC)cc1F

InChI Key InChIKey=OBEJJFJTFKBHKP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50544085   

TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544085(CHEMBL4642177)
Affinity DataIC50: 208nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544085(CHEMBL4642177)
Affinity DataIC50: 663nMAssay Description:Inhibition of EGFR 19D/T790M/C797S mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544085(CHEMBL4642177)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544085(CHEMBL4642177)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed