BDBM50544216 CHEMBL4649382

SMILES CN1CCC(CC1)C(=O)N[C@@H](CCCCCC(=O)c1ccccn1)c1ncc([nH]1)-c1ccccc1

InChI Key InChIKey=NBHIUHBQRKSJFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50544216   

TargetHistone deacetylase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50544216(CHEMBL4649382)
Affinity DataIC50: 150nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells using FLUOR DE LYS as substrate preincubated for 3 hrs follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50544216(CHEMBL4649382)
Affinity DataIC50: 240nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using FLUOR DE LYS as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50544216(CHEMBL4649382)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using FLUOR DE LYS as substrate preincubated for 3 hrs followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed