BDBM50544361 CHEMBL4635542

SMILES Cc1ccc2[nH]c(C(=O)N[C@H]3CN(S(=O)(=O)c4ccccc4)C[C@@H]3C(=O)NC[C@@H]3CCCN3C)cc2c1

InChI Key InChIKey=FYMCVLGQQUJCDI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544361   

TargetGrowth hormone secretagogue receptor type 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544361BDBM50544361(CHEMBL4635542)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544361BDBM50544361(CHEMBL4635542)
Affinity DataEC50:  0.168nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed