BDBM50544373 CHEMBL4641215

SMILES Cc1nc(sc1C(=O)N[C@H]1CN(C[C@@H]1C(=O)N[C@H]1CCCNC1)S(=O)(=O)c1ccccc1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=XOWKYWXMJYXVEB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544373   

TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544373(CHEMBL4641215)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544373(CHEMBL4641215)
Affinity DataEC50:  7.94nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed