BDBM50544438 CHEMBL4635765::US11192850, Entry 4r
SMILES OC(=O)C(=O)Nc1ccc(cc1)C#Cc1ccc(OCc2ccccc2)cc1
InChI Key InChIKey=KETZCULIMWCEFD-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50544438
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of SHP2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis s...More data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+4nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Purdue Research Foundation
US Patent
Purdue Research Foundation
US Patent
Affinity DataIC50: 38nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+4nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+4nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair