BDBM50544615 CHEMBL4633358

SMILES CNCCCOc1cc2c3n(C(C)c4ccccn4)c(=O)n(C)c3cnc2cc1-c1c(C)noc1C

InChI Key InChIKey=UHXICNQEYQYKEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544615   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50544615(CHEMBL4633358)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant expressed in Escher...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50544615(CHEMBL4633358)
Affinity DataIC50:  2.51E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled I-BET762 from N-terminal His6-tagged human BRD4 BD2 (1 to 477 residues)/BD1 Y97A mutant expressed in Escheri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed