BDBM50544639 CHEMBL4637519

SMILES CCCCC(=O)N(Cc1ccc(cc1)-c1ccccc1C(O)=O)c1ccccc1

InChI Key InChIKey=IUJTVDNJFPZYBL-UHFFFAOYSA-N

Data  2 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50544639   

TargetLeukotriene B4 receptor 2(Human)
Incerebro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544639BDBM50544639(CHEMBL4637519)
Affinity DataKd:  15nMAssay Description:Displacement of [3H]LTB4 from HA-epitope tagged human BLT2 expressed in CHOK1 cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Incerebro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544639BDBM50544639(CHEMBL4637519)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Incerebro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544639BDBM50544639(CHEMBL4637519)
Affinity DataIC50: 63nMAssay Description:Displacement of FITC-labeled tracer from Lumi4 Tb-labeled BLT2 (unknown origin) expressed in CHO-K1 cells incubated for 1 hrs by Tag-lite displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544639BDBM50544639(CHEMBL4637519)
Affinity DataIC50: 5.30E+4nMAssay Description:Antagonist activity at human AT1 receptor expressed in CHO-K1 cells co-expressing GNA14 assessed as inhibition of Val5-Angiotensin-II induced IP-1 ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed