BDBM50544902 CHEMBL4639231

SMILES Cc1cnc(NS(=O)(=O)c2ccc(Nc3ccnc(SCC(=O)c4ccc(cc4)C(F)(F)F)n3)cc2)nc1

InChI Key InChIKey=OEUIIKNJVOUWTK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50544902   

TargetCarbonic anhydrase 9(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50544902(CHEMBL4639231)
Affinity DataKi:  490nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red dye based stopped-flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50544902(CHEMBL4639231)
Affinity DataKi:  6.44E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red dye based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50544902(CHEMBL4639231)
Affinity DataKi:  5.91E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red dye based stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50544902(CHEMBL4639231)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red dye based stopped-flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed