BDBM50544981 CHEMBL4649793

SMILES CN1CCN(CC1)C(=O)c1ccc(\C=C2/SC(=S)N(C2=O)c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=AIGFDRHMPBDTIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544981   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50544981(CHEMBL4649793)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophage cells assessed as effect on IL-1beta produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed