BDBM50545022 CHEMBL4632758

SMILES O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc4c(n3)CN(CCN3CCOCC3)C43CCOCC3)c21

InChI Key InChIKey=NNTRWHBIVTUJEX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50545022   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 2.70nMAssay Description:Agonist activity at mouse PPARgamma assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 183nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 553nMAssay Description:Agonist activity at human PPARgamma assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetTyrosine-protein kinase ZAP-70(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetTyrosine-protein kinase SYK(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at human PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetTyrosine-protein kinase JAK1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARgamma assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at human PPARgamma assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetTyrosine-protein kinase Fyn(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetTyrosine-protein kinase Lyn(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at human PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetTyrosine-protein kinase Lck(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
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TargetMisshapen-like kinase 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at human PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
Copy reaction URL

TargetInterleukin-1 receptor-associated kinase 4(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50545022(CHEMBL6091847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
Copy reaction URL