BDBM50545032 CHEMBL4639103

SMILES CN1CCC2(CC1)c1ccc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)nc1CN2C

InChI Key InChIKey=SJCXMSPWWXYJRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545032   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545032BDBM50545032(CHEMBL6078343)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human PPARgamma receptor in CHO-K1 cells assessed as rosiglitazone-induced receptor activation by cell based reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545032BDBM50545032(CHEMBL6078343)
Affinity DataIC50: 279nMAssay Description:Agonist activity at human PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed