BDBM50545079 CHEMBL4635807

SMILES [H][C@]1(Cc2ccc(OCCCCCCCC(=O)N[C@@H](Cc3c[nH]cn3)C(=O)N1)cc2)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

InChI Key InChIKey=JRCPIIDXDIJIHX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545079   

LigandPNGBDBM50545079(CHEMBL4635807)
Affinity DataIC50: 550nMAssay Description:Inhibition of His6-tagged human SIRT3 deacetylation activity using SIRT3 acetyl-lysine as substrate substrate in presence of beta-NAD+ after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50545079(CHEMBL4635807)
Affinity DataIC50: 673nMAssay Description:Inhibition of His6/GST-tagged human SIRT1 deacetylation activity using SIRT1 acetyl-lysine as substrate in presence of beta-NAD+ after 10 mins by rev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50545079(CHEMBL4635807)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of His6-tagged human SIRT2 deacetylation activity using SIRT1 acetyl-lysine as substrate in presence of beta-NAD+ after 12 mins by reverse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed