BDBM50545525 CHEMBL4640049

SMILES C[C@@H]1C[C@@H](CN(C1)c2ncc(c(n2)Nc3ccc4c(c3)C=C(C(=O)N4C)OCC(=O)NC)Cl)C

InChI Key InChIKey=GXTJETQFYHZHNB-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545525   

TargetB-cell lymphoma 6 protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50545525(CHEMBL4640049)
Affinity DataIC50: 3nMAssay Description:Inhibition of BCL6 BTB domain (5 to 129 residues) (unknown origin) expressed in Escherichia coli using 5-TAMRA-RSEIISTAPSSWVVPGP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMaternal embryonic leucine zipper kinase(Human)
Cedilla Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545525(CHEMBL4640049)
Affinity DataIC50: 200nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed