BDBM50545550 CHEMBL4637025

SMILES OC(=O)Cc1cc(Br)c(Oc2cc(I)c(O)c(I)c2)c(I)c1

InChI Key InChIKey=KTERKZCXUGODHD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545550   

TargetThyroid hormone receptor beta(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50545550(CHEMBL4637025)
Affinity DataEC50:  19nMAssay Description:Agonist activity at THRbeta (unknown origin) incubated for 14 to 16 hrs by dual glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50545550(CHEMBL4637025)
Affinity DataEC50:  30nMAssay Description:Agonist activity at THRalpha (unknown origin) incubated for 14 to 16 hrs by dual glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50545550(CHEMBL4637025)
Affinity DataEC50:  300nMAssay Description:Agonist activity at recombinant human pFA-CMV fused PPARgamma expressed in HEK293T cells transfected with pFR-luciferase plasmid and pRL-SV40 plasmid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed