BDBM50545625 CHEMBL4639774

SMILES CN(C1CCCCC1)c1nc(Nc2ccc(cc2)C(N)=O)ncc1C

InChI Key InChIKey=MHTFQIBQBHDDQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545625   

TargetTyrosine-protein kinase JAK3(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545625(CHEMBL4639774)
Affinity DataIC50: 44nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545625(CHEMBL4639774)
Affinity DataIC50: 340nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human Lck using TK-substrate-biotin as substrate incubated for 60 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed