BDBM50545661 CHEMBL4649820

SMILES Cc1cccc(C)c1-c1cnc2c(c1)C[C@@]1(OCCCc3ccccc3)[C@H]3Cc4ccc(O)c5c4[C@@]1(CCN3CC1CC1)[C@H]2O5

InChI Key InChIKey=HHPBPMMGXGLFBZ-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50545661   

TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545661BDBM50545661(CHEMBL4649820)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545661BDBM50545661(CHEMBL4649820)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membranes assessed as reduction in SNC80-induced [35S]GTPgammaS binding prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545661BDBM50545661(CHEMBL4649820)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545661BDBM50545661(CHEMBL4649820)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545661BDBM50545661(CHEMBL4649820)
Affinity DataKi:  249nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed