BDBM50545662 CHEMBL4644691

SMILES COc1ccccc1-c1cnc2c(c1)C[C@@]1(OCCCc3ccccc3)[C@H]3Cc4ccc(O)c5c4[C@@]1(CCN3CC1CC1)[C@H]2O5

InChI Key InChIKey=BESXJJIHQREVRG-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50545662   

TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545662BDBM50545662(CHEMBL4644691)
Affinity DataIC50: 0.790nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membranes assessed as reduction in SNC80-induced [35S]GTPgammaS binding prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545662BDBM50545662(CHEMBL4644691)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545662BDBM50545662(CHEMBL4644691)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545662BDBM50545662(CHEMBL4644691)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545662BDBM50545662(CHEMBL4644691)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed