BDBM50545668 CHEMBL4641271

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(Cc1cc(cnc21)-c1ccc(cc1)N(C)C)OCCCc1ccccc1)ccc3O

InChI Key InChIKey=YXBNXFSNSLDHKY-BPSUTHQGSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50545668   

TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545668(CHEMBL4641271)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545668(CHEMBL4641271)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545668(CHEMBL4641271)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545668(CHEMBL4641271)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membranes assessed as reduction in SNC80-induced [35S]GTPgammaS binding prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545668(CHEMBL4641271)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed