BDBM50545680 CHEMBL4647357

SMILES Oc1ccc2c3c1O[C@H]1c4ncc(-c5cncnc5)cc4C[C@@]4(OCCCc5ccccc5)[C@@H](C2)N(CC2CC2)CC[C@]314

InChI Key InChIKey=XYOJXTMPYSHNJG-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50545680   

TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545680BDBM50545680(CHEMBL4647357)
Affinity DataIC50: 0.870nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membranes assessed as reduction in SNC80-induced [35S]GTPgammaS binding prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545680BDBM50545680(CHEMBL4647357)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545680BDBM50545680(CHEMBL4647357)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545680BDBM50545680(CHEMBL4647357)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545680BDBM50545680(CHEMBL4647357)
Affinity DataEC50: >3.33E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed