BDBM50546407 CHEMBL4740065

SMILES Cn1ccc2c(cccc12)-c1nc2c(ccnc2[nH]1)-n1cc(N[C@@H]2CCOC[C@@H]2N)cn1

InChI Key InChIKey=MXZJNQSPLXUEQL-ZWKOTPCHSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50546407   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of human ERG assessed as tail current by plate-based planar patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB