BDBM50547251 CHEMBL4785221

SMILES CN1CCN(CC1)c1ccc(cc1)-c1[nH]c2ncn(C)c(=O)c2c1-c1cccc(NC(=O)C=C)c1

InChI Key InChIKey=SCPXIXAJVMGIOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547251   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547251BDBM50547251(CHEMBL4785221)
Affinity DataIC50: 146nMAssay Description:Inhibition of C-terminal His6-tagged HER2 (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed