BDBM50547253 CHEMBL4759651

SMILES CC(C)n1cnc2[nH]c(c(-c3cccc(NC(=O)C=C)c3)c2c1=O)-c1ccc(cc1)N1CCN(C)CC1

InChI Key InChIKey=CDHCIFPMFKCLCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547253   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547253BDBM50547253(CHEMBL4759651)
Affinity DataIC50: 592nMAssay Description:Inhibition of C-terminal His6-tagged HER2 (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed